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diagnosis hematology algorithm generalized oncology secondary systemic classification disorders extravascular hemeonc hemolysis hemolytic hemophagocytic hlh hodgkins intravascular leukemia lymphohistiocytosis lymphoma
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Causes == Primary ... renal failure/uremia ... parasitosis #Pruritus ... #generalized #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelogenous Leukemia • Primary ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Platelet Disorders - Differential ... changes), high MCV anemia ... unclear, or if a primary ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... /Quantity: • Primary ... Causes: - Thrombocytopenia ... - Hemolytic anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... usually IgM) (e.g. primary ... #differential # ... #anemia
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... parasitosis #Pruritus ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... sweats, bleeding • Pruritis ... - infiltrates (anemia ... , thrombocytopenia ... + distinctive primary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... • Pruritis ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Types of HLH • Primary ... - Cytopenias (anemia ... , thrombocytopenia ... #Hematology #HemeOnc
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