8 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatomegaly and anemia ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
(SAAG) - Differential ... - Alcoholic hepatitis ... Veno-occlusive disease - Acute ... fatty liver of ... Diagnosis #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... Septic shock, Obstetric ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... ) estimated by gradient ... HTN: ascites (SAAG ... • Cirrhosis/acute ... hepatitis • Infiltrative
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology ... #obstetrics #obgyn
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Alcoholic hepatitis ... fibrosis - Acute ... fatty liver of ... Causes #diagnosis #differential ... #hepatology #SAAG
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Viral infections (acute ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... inflammation (acute ... Gap #ProteinGap #differential