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management neurology differential hematology dermatology guillain acromegaly acute amyloid amyloidosis anemia antibodies aplastic bee capillary cauda caudaequina cerebritis chronic clarksons
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Clinical Features ... Diagnosis: • ... axonal form • MRI ... #Syndrome #diagnosis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
, TIF1y, NXP2, Mi ... -2, SAE Anti-Synthetase ... Syndrome: Jo-1, ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... - Spinal MRI may ... and cauda equina TREATMENT ... #Syndrome #diagnosis
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... and treatment can ... Non-inflammatory causes ... neuropathy (LHON) plus MRI ... lesions and clinical
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... cord • Guillain-Barre ... Imaging studies: • MRI ... axial T1 and T2 Treatment ... #causes #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
: • A clinical ... out other causes ... - MRI: inflammation ... and lower jaw Treatment ... #Rheumatology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Vascular narrowing on MRA ... epilepticus Treatment ... the underlying cause ... • Treatment of ... with AEDs until cause
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... infections (Epstein-Barr ... syndrome, HIV)
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