30 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
, TIF1y, NXP2, Mi ... -2, SAE Anti-Synthetase ... Syndrome: Jo-1, ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... signs of end organ damage ... • Treatment: ... #TLS #diagnosis ... #management #hematology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... and treatment can ... Non-inflammatory causes ... neuropathy (LHON) plus MRI ... lesions and clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
and end-organ damage ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad ... classification #rheumatology
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
consistent with a diagnosis ... the result of damage ... experience, the cause ... or induced by treatment ... #clinical #video
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... axonal form • MRI ... #treatment #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct Damage ... Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... uveitis or retinal damage ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
: • A clinical ... out other causes ... - MRI: inflammation ... and lower jaw Treatment ... #Rheumatology #