31 results
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... opsonize pathogen (tag ... #Inflammation #pathophysiology ... #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Pathogenesis and clinical ... self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... exposure to allergen causes ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... cell-dependent Ag ... : Ag-presenting ... Humoral #Immunity #pathophysiology ... #immunology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... HTN: ascites (SAAG ... Post-Hepatic: • Cardiac causes ... Differential #Diagnosis #causes ... #hepatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Cytopenia: Common • Immunologic ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... drug-dependent) • Immunologic ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Cytopenia: Common • Immunologic
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Maternal Support - Critical ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... to produce all classes ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology