6 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Differential Diagnosis ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... - Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Hyperparathyroidism • Hypercalcemia ... Pituitary path • Acromegaly ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Tall Stature - Differential ... Puberty Onset • GH ... Resistance • Acromegaly ... #TallStature #Differential ... Diagnosis #Algorithm #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... disorders including hypokalemia ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly ... Workup #causes #Differential