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diagnosis ketoacidosis diabetes comparison differential disorders dm2 hyperglycemic ketones ketosis algorithm crisis ddxof diabeticketoacidosis dosing dpp4 em endo eudka euglycemic
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
) • Diabetic Ketoacidosis ... Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... (DKA) and Hyperglycemic ... Hyperosmolar Syndrome (HHS ... #hhs #pathophysiology ... #comparison #endocrinology
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Diabetic Ketoacidosis ... and Management ... ) pH > 7.3 3) AG ... #Diagnosis #Management ... #Endocrinology
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Diabetic Ketoacidosis ... and Management ... ) pH > 7.3 3) AG ... #Diagnosis #Management ... #Endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... patients with diabetes ... Key signs/symptoms ... of HHS/DKA: Both ... #HHS #Ddxof
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Diabetic ketoacidosis ... seen with SGLT inhibitors ... • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Stepwise Approach to Prescription of SGLT2 inhibitors Anticipatory Guidance • Consider diuretic dose reduction Patient Counseling
Prescription of SGLT2 inhibitors ... Guidance • Consider diuretic ... • Symptoms Of DKA ... Prescribing #Monitoring #Management ... #Endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
Algorithm for DKA ... /HHS Diagnostic ... Crisis #Algorithm #management ... #endocrinology ... #Diabetes #DM2 #
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
Euglycemic Diabetic ... (EuDKA) SGLT2 Inhibitors ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
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