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diagnosis hematology leukemia ana antinuclear autoantibodies cll differentiation lupus lymphocytic management mds myelodysplasia myelodysplastic syndromes systemic workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... #APML #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Richter’s Syndrome ... leukemia #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
SLE-SSc-AlM overlap syndromes ... diseases only if Ag ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Marrow Failure • Chronic ... progression to AML ... #diagnosis #hematology ... #oncology
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