12 results
diagnosis differential hematology algorithm oncology secondary generalized mds pruritus systemic treatment aplastic atopic atopy b12 cobalamin deficiency dermatitis eczema gap
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... renal failure/uremia ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... #generalized #dermatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... vera (PV) • Myelodysplastic ... Chronic myeloid leukemia ... #hematology #secondary
Pustular Skin Rash - Differential Diagnosis Algorithm Pruritic / Scaly / Erythematous lesions, usually poorly demarcated Acneiform -
Pustular Skin Rash ... body folds with satellite ... #Pustular #SkinRash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Out Secondary Causes ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... • Hypocellular myelodysplastic ... virus (EBV) • Leukemia ... #diagnosis #management
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... -> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... , yellow skin, cognitive ... palpitations), skin ... diagnosis e.g. leukemia ... Deficiency #diagnosis #management
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