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oncology differential hematology algorithm causes generalized mds secondary systemic aplastic clinical cutaneous leukemia manifestations myelodysplasia primary pustular syndromes treatment
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... most frequent skin ... polymorphism • Satellite ... #diagnosis #dermatology ... oncology #clinical #skin
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... Diagnosis and Management ... cytopenias (usually anemia ... #Diagnosis #Management
Pustular Skin Rash - Differential Diagnosis Algorithm Pruritic / Scaly / Erythematous lesions, usually poorly demarcated Acneiform -
Pustular Skin Rash ... Algorithm Pruritic ... body folds with satellite ... #Pustular #SkinRash ... #dermatology #Differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Skin Lesion - Differential ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... just beneath the skin ... • Aplastic Anemia ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... • Hypocellular myelodysplastic ... syndrome (MDS) ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... - infiltrates (anemia ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Oncology #Diagnosis
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