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diagnosis hematology syndrome apml clinical common comparison cutaneous differentiation distribution manifestations monoclonal myelodysplastic paraproteinemias primarycare rash scleroderma table
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
polymorphism • Satellite ... Neutrophilic dermatosis ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
scale • Basal cell ... • Squamous cell ... macerated areas with satellite ... ; pruritis #dermatology ... #rash #differential
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... : - Indurated plaques ... large numbers of stellate ... hematopoietic stem cell ... comparison #table #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... • Neutrophilic dermatosis ... #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... febrile neutrophilic dermatosis ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
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