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diagnosis hematology differential leukemia antinxp2 antinxp2dm chronic clinical dermatomyositis lymphocytic manifestations monoclonal myelodysplastic paraproteinemias rheumatology sweet workup
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... polymorphism • Satellite ... differential #diagnosis #dermatology ... #oncology #clinical ... #skin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
violaceous, nontender cutaneous ... plaques) AML Dx ... • Tumor lysis syndrome ... -> Invade Skin: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... macules, papules, plaques ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
) is a skin condition ... Most common extra cutaneous ... general feeling of ill ... #diagnosis #dermatology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... gangrenosum • Cutaneous ... thrombosis+Pulm HTN+skin ... Differential #Diagnosis #Oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... have typical DM skin ... Violaceous papules or plaques ... Dermatomyositis #diagnosis #management ... #rheumatology #dermatology
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