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diagnosis differential oncology rheumatology clinical hematology monoclonal antinxp2 antinxp2dm behcet dermatomyositis disease gammopathy immune inflammatory iris leukemia monkeypox mpox myelodysplastic
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... polymorphism • Satellite ... Calmettes #Cutaneous ... differential #diagnosis #dermatology
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... , Syndrome Schnitzler ... monoclonal #gammopathy #Cutaneous ... #manifestations ... #dermatology #skin
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Manifestations: ... gangrenosum • Cutaneous ... Neurologic Manifestations ... thrombosis+Pulm HTN+skin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
M > F Clinical Manifestations ... vasculitis) • Cutaneous ... response to local skin ... test (this is a skin ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... • Pustular skin ... Osteoarticular manifestations ... Rheumatology #diagnosis #management ... #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... : CNS manifestations ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... CLL -> Invade Skin
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
activity • Via cutaneous ... mpox had ocular manifestations ... Complications: • Cutaneous ... MPOX #Diagnosis #Management ... #Dermatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical manifestations ... cavitating pneumonia, skin ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... have typical DM skin ... ulcerations • Skin ... Dermatomyositis #diagnosis #management ... #rheumatology #dermatology
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