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diagnosis differential rheumatology hematology anemia aplastic classification clinical cutaneous dermatologic granulomatosis joint manifestations monoclonal myelodysplastic nonpalpable pain palpable paraproteinemias polyangiitis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... polymorphism • Satellite ... dermatosis: Sweet's syndrome ... myelodysplastic #syndrome ... #oncology #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Skin lesions ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... lesions • Discoid ... Sarcoidosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lesions • Mononeuritis ... Mucocutaneous lymph node syndrome ... mucositis - Rash ... : • Behçet Syndrome ... • Cogan Syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... - GPA - EGPA
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... classical Sweet syndrome ... - Schnitzler’s syndrome ... #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... , mucositis • Rash ... : • Skin lesions ... • Behcet syndrome ... • Cogan syndrome
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... Generalized itchy rash ... SAPHO syndrome ( ... Sweet syndrome ... #Diagnosis #Dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... CVST • Bing-Neel syndrome ... (Dermato-neuro syndrome ... dermatosis) • Gleich syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #management
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