22 results
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
CLINICAL MANIFESTATIONS ... mild normocytic anemia ... : - Pale skin ... without marked anemia ... Insufficiency #Signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... #Differential #diagnosis
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... E - Haemolytic anaemia ... - Coagulation disorder ... #differential #diagnosis ... #signs #symptoms
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Viral Infection Clinical ... of anemia include ... anemia • Cold ... #hematology #diagnosis
Symptoms and Signs of Hypocalcemia
Muscular: Weakness, fatigue, Spasms, cramps
Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... Extrapyramidal disorders ... Dermatologic: ... hair, Dry, scaly skin ... #Signs #diagnosis
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive Disorder ... Pathogenesis and Clinical ... /pleasure) - Anergia ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... integrity of: • Skin ... poor nutrition Clinical ... Psychiatric symptoms ... Loss of teeth Anemia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... minimal tumor burden Diagnosis ... immunophenotype Clinical ... marrow failure with anemia ... #hemeonc #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... , yellow skin, cognitive ... palpitations), skin ... , alcohol use, symptoms