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hematology differential oncology management causes signs algorithm pathophysiology rheumatology workup leukemia nutrition chronic classification cll cold deficiency erythematosus hemeonc lupus
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Lymphoproliferative disorder ... , Autoimmune disorder ... #Anemia #hematology ... #diagnosis #comparison
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
of Hemolytic Anemia ... Pathophysiology #Hemolytic ... #Anemia #hematology ... #diagnosis #signs ... #symptoms
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... lymphoproliferative disorders ... #differential #diagnosis ... #hematology #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... Cold autoimmune hemolytic ... #differential #diagnosis ... #hematology #microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider RBC membrane disorder ... #Anemia #Differential ... #workup #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... anemia, PNH, immune ... paralyses CNS Disorders ... associated with any symptoms ... #differential #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... anaemia, ataxia ... - Coagulation disorder ... #differential #diagnosis ... #signs #symptoms
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... #Causes #hematology
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