15 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
, Rivaroxaban, Apixaban ... Anticoagulants #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
(Praxbind) - Apixaban ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Rivaroxaban • Apixaban ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... Mechanisms #DOAC #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... management #algorithm #pharmacology ... decisionaid #cardiology #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
diagnosis #models #hematology ... pathophysiology #anticoagulation ... thrombin #inhibitor #Apixaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Very Quick Guide to Reversing Antithrombotic Therapy
Aspirin 
Clopidogrel 
Prasugrel 
Ticagrelor 
Abciximab 
Tirofiban 
Eptifibatide 
Unfractionated Heparin 
Low
Dabigatran Apixaban ... Antithrombotic #Anticoagulation ... Antiplatelet #Management #Hematology