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hematology doac anticoagulation noac anticoagulant diagnosis management oral dabigatran dosing edoxaban reversal anemia anticoagulants bridging cheatsheet chemotherapy chronic cll cyp3a4
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology ... #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... Anti-Coagulants • Rivaroxaban ... • Apixaban ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... anticoagulation #Switching #hematology ... #pharmacology
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
(Praxbind) - Apixaban ... Edoxaban (Lixiana), Rivaroxaban ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... 60kg, CrCl 15-50 Rivaroxaban ... Anticoagulation #Hematology ... #Pharmacology # ... Apixaban #Rivaroxaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
, and apixaban are ... Rivaroxaban and ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... #Anemia #oncology ... #hematology #diagnosis
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... anticoagulant #hematology ... #management #pharmacology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Pure red cell aplasia ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Causes • Anemia • Aplastic ... Syndromes #diagnosis #hematology ... #oncology
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