11 results
diagnosis hematology oncology differential algorithm causes secondary generalized management mds pruritus systemic anemia aplastic cancer chronic clinical cll cutaneous gap
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... most frequent skin ... polymorphism • Satellite ... #diagnosis #dermatology ... oncology #clinical #skin
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... transformation to acute leukemia ... #Syndrome #MDS ... Management #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... Diagnosis #Causes #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
• Xerosis (dry skin ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic ... just beneath the skin ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Hepatomegaly • Skin ... • Richter’s Syndrome ... • Sezary syndrome ... workup #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... • Hypocellular myelodysplastic ... syndrome (MDS) ... virus (EBV) • Leukemia ... Anemia #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... differential #diagnosis #hematology
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