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hematology anticoagulation noac anticoagulant algorithm cancer diagnosis malignancy oncology oral reversal treatment vte bridging causes coagulation dic direct disseminated hemeonc
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
direct-acting oral anticoagulants ... direct-acting oral anticoagulant ... molecular weight heparin ... Anticoagulation #Management ... #Hematology #Oncology
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 DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... #Oral #anticoagulant ... #hematology #management ... #pharmacology
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... assay; ECT = ecarin ... thrombin time #doac ... #hematology #laboratory ... #testing #aptt
Anticoagulant Bridging • Switching from LMWH • Switching from UFH • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... from Warfarin to DOAC ... anticoagulation #pharmacology ... #management #hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... low-molecular-weight heparin ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Reduction of pro/anticoagulants ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... arterial thrombosis, skin ... exposure (prevent skin ... , Bivalirudin, DOAC ... #Treatment #Hematology
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