11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... #Loading #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
VTE and Renal Dosing ... Renal Dosing ... Anticoagulation #Hematology ... #Pharmacology # ... Dabigatran #Edoxaban #NOAC
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... synchronous or appearing during ... polymorphism • Satellite ... differential #diagnosis #dermatology ... oncology #clinical #skin
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
the treatment of cancer-associated ... for appropriate dosing ... filtration rate; DOAC ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... bleeding risk during ... DOAC, direct oral ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... content/133/4/291 #DOAC ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... gastric and breast cancer ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... leukemia • Lung cancer ... • Cervical cancer
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology