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diagnosis hematology oncology anticoagulation bleed chads2 chads2vasc hasbled risk score stroke anemia aplastic cryofibrinogenemia disorders dress history leukemia management mds
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas #Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... #Diagnosis #Hematology ... CHADS2VASc #HASBLED #Comparison ... Anticoagulation #AFib
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 DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... involvement with bleeding ... Prerenal azotemia • Skin ... #SJS #TEN #comparison ... #table #dermatology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
S Stroke 1 B Bleeding ... CHADS2VASc #HASBLED #Comparison ... Anticoagulation #AFib ... #Diagnosis #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
night sweats, bleeding ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... Antiphospholipid syndrome ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... ecchymoses, mucosal bleeding ... Constitutional Syndromes ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... unusual bruising or bleeding ... just beneath the skin ... are caused by bleeding ... #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
in Evaluating Bleeding ... haemophilias, bleeding ... and skin haemorrhage ... Marfan syndrome, ... pediatrics #diagnosis #hematology
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