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diagnosis dermatology differential rheumatology anaphylaxis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune common disorders distribution eosinophil eosinophilia hematology management manifestations myopathy myositis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... are asthma, allergy ... organ-specific signs ... symptoms (eg, skin
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... CANDLE syndrome - Allergic
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
tongue and lips - Skin ... : urticarial rash ... , morbilliform rash ... play #Diagnosis #Allergy ... #Signs #Symptoms
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 Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... #causes
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... Deep vesicles • Allergic ... honey-colored crusts ... macerated areas with satellite ... #dermatology #rash
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused
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