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diagnosis dermatology differential rheumatology myositis vasculitis antimda5 antimda5dm antinxp2 antinxp2dm classification common distribution erythematous febrile fever management myopathy nikolsky oncology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Dermatomyositis ... , Shaw sign, holster ... sign, and Gottron's ... anti-synthetase syndrome
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... syndrome (SSS) ... the Nikolsky sign ... fever or Nikolsky sign
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... #causes
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... on sun-damaged skin ... honey-colored crusts ... macerated areas with satellite ... #dermatology #rash
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... , mucositis • Rash ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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