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differential dermatology symptoms rheumatology pathophysiology vasculitis allergy anaphylaxis gca maculopapular management skinrash aion anteriorischemicopticneuropathy antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #dermatology #diagnosis
Pustular Skin Rash - Differential Diagnosis Algorithm Pruritic / Scaly / Erythematous lesions, usually poorly demarcated Acneiform -
Pustular Skin Rash ... - Differential Diagnosis ... Algorithm Pruritic ... body folds with satellite ... #Algorithm #causes
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... the Nikolsky sign ... erythematous rash ... fever or Nikolsky sign
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of ... tongue and lips - Skin ... : urticarial rash ... cessation of play #Diagnosis ... #Allergy #Signs
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 Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm Face • Melasma Abdomen • Linea Nigra Hormone induced
- Differential Diagnosis ... Algorithm Face ... • Chadwick's sign ... #Differential #Diagnosis ... #Algorithm #causes
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
Clinical manifestations ... (Skin and Mucosa ... arrest GI (>40%): Nausea ... #anaphylaxis #signs ... #symptoms #diagnosis
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Extrapulmonary manifestations ... Gastrointestinal: Diarrhea, Nausea ... , Erythematous rash ... Extrapulmonary #Diagnosis ... #Signs #Symptoms
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