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diagnosis lupus sle causes complications dermatomyositis differential disease dm erythematosus extraarticular heatstroke illness kawasaki manifestations mucocutaneous pm polymyositis ra rheumatoidarthritis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
• Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Rash: • Small ... blisters on the skin ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... blood vessels (vasculitis ... (Xerostomia) Heart ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
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