7 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... multiforme - Dermatomyositis ... Leukocytoclastic vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... rash (Gottron papules ... and Gottron sign ... ) • Shawl sign