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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... - GI tract: abdominal ... Presentation - Systemic Symptoms ... purpura: strong sign ... Supply gut -> abdominal
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... tract, and often causes
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries
Takayasu's arteritis:
 - Onset < 40 yrs
 -
yrs - Cranial symptoms ... Polyarteritis nodosa: - Skin ... nodules, livedo - Abdominal ... sinusitis - pulmonary ... Coronaries #Arteritis #Differential
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
(Skin and Mucosa ... arrest, Kounis syndrome ... intestinal edema, abdominal ... #anaphylaxis #signs ... #symptoms #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Behcet disease) Differential ... • Nonsurgical abdominal ... diagnosis #management #signs ... #symptoms #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... clinical context and signs ... Glomerulonephritis / Vasculits ... renal biopsy • Abdominal ... compartment syndrome
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
Rare Causes of Abdominal ... - May involve symptoms ... neuropsychiatric symptoms ... Positive Carnett's sign ... #differential #
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... Back pain • Skin ... changes • Urinary symptoms ... • Budd-Chiari syndrome ... #Differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... inflammation tends to cause ... interstitial lung disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis