12 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... Autoimmune manifestations ... differential #diagnosis #dermatology ... oncology #clinical #skin
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Diagnosis Algorithm Signs ... Hemolysis: • Autoimmune ... Anemias (AIHAs) • Alloimmune ... Diagnosis #Algorithm #hematology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
Pyoderma Gangrenosum: Autoimmune ... ulceration of the skin ... Goldberg, M.D. - UCSD ... Clinical #Photo #Dermatology ... #Gangrenosum #UCSDH
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... LcSSc) - distal skin ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Vascular reactivity (Skin ... associated with autoimmune ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
associated with signs ... on sun-damaged skin ... macerated areas with satellite ... Acrochordons (skin ... ; pruritis #dermatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... three days #AntiNXP2DM ... diagnosis #management #rheumatology ... #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... workup #oncology #hematology