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differential hematology systemic addisons adrenal cryofibrinogenemia disease endocrinology erythematosus hemeonc hemophagocytic hlh insufficiency lupus lymphohistiocytosis management myopathy myositis pathophysiology scleroderma
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... and Symptoms: ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... / Symptoms: - ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... Serum DHEAS Diagnosis ... patches on the skin ... endocrinology #diagnosis ... #signs #symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Primary (essential ... associated with autoimmune ... Cryofibrinogenemia Diagnosis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... • Progressive symptoms ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... rheumatologic diseases ... the context of primary ... Induced Lupus: • Symptoms ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • Primary ... Malignancies ▪ Autoimmune ... Presentation • Common Signs ... and Symptoms: ... #Management #Hematology
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