9 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... Multi-system autoimmune ... thickening Signs ... #Sclerosis #Scleroderma ... #SSc #rheumatology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... @AnnKumfer #Systemic ... #Sclerosis #Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
sclerosis/scleroderma ... sclerosis/scleroderma ... sclerosis/scleroderma ... Sclerosis (scleroderma ... ANA #patterns #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... TIF1y, MDA5 • Scleroderma ... (Systemic Sclerosis ... Autoantibodies #Rheumatology ... #associations #table
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Scleroderma Like ... treatment Nephrogenic Systemic ... large numbers of stellate ... Diagnosis #comparison #table ... #dermatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
exudates) - SLE • Scleritis ... Telangiectasia • Scleroderma ... Thickened skin ... • Scleroderma ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
central nervous system ... Presentation - Systemic ... , particularly scleritis ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... Presentation: Systemic ... , particularly scleritis ... purpura: Strong sign ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... Myositis #Myopathy #rheumatology