9 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Systemic #Lupus #Erythematosus ... Summary #diagnosis #rheumatology ... #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
associated with signs ... on sun-damaged skin ... macerated areas with satellite ... dimpling of overlying skin ... Acrochordons (skin
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
with edema • Erythematous ... chest (in a V-sign ... ulcerations • Skin ... violaceous macules and erythematous ... Dermatomyositis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... : erythematous nodules ... systemic lupus erythematosus ... purpura: strong sign ... differential #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... test (this is a skin ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... : Erythematous nodules ... cmpkx deposits skin ... Differential #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... chest (in a V-sign ... shoulders (in a shawl sign ... Dermatomyositis #diagnosis #management ... #rheumatology #