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diagnosis symptoms differential erythematosus joint lupus management sle systemic arthritis behcet conditions cryoglobulinemia dermatology disease extraarticular extrarticular gca giantcell pathophysiology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... - 10% SLE or RA ... reticularis & skin ... diagnosis #types #classification ... #rheumatology #
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Hypersensitivity vasculitis ... gangrenosum • IBD • RA ... dermatology #joint #pain ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... conditions #joint #pain ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
purpura: strong sign ... , testes -> pain ... Serologies for Cryoglobulins ... differential #diagnosis #rheumatology ... #classification
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... (RA): Extra-articular ... manifestations Skin ... blood vessels (vasculitis ... pathophysiology #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... GCA (Giant Cell Arteritis ... tract: Abdominal pain ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... response to local skin ... Nonsurgical abdominal pain ... diagnosis #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... Complications of DMARDs • Skin ... Vascular: Rheumatoid vasculitis ... #RA #Signs #Symptoms ... #diagnosis #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... systemic sx + signs ... claudication: pain ... required due to skip ... them, but urgent rheumatology
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