6 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... - 10% SLE or RA ... lupus erythematosus ... classification #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Behçet Syndrome ... lupus erythematosus ... purpura: strong sign ... Serologies for Cryoglobulins ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... polychondritis, Behcet's ... Rheumatoid Arthritis (RA ... ), Systemic lupus ... Differential #Diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... , small-vessel vasculitis ... response to local skin ... #management #signs ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology