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diagnosis differential classification erythematosus lupus management pain sle symptoms systemic arthritis conditions cryoglobulinemia cryoglobulins dermatology extrarticular myopathy myositis polychondritis rashes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... gangrenosum • IBD • RA ... Antiphospholipid-antibody syndrome ... • Vasculitis ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... Heberden's nodes (DIP joints ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... infection • Autoimmune ... - 10% SLE or RA ... reticularis & skin ... classification #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... : • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Complications of DMARDs • Skin ... Vascular: Rheumatoid vasculitis ... Musculoskeletal: Joint ... Rheumatoid #Arthritis #RA ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... vesicular eruption • Joints ... Palpable purpura, joint ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... disease • Non-autoimmune ... rheumatologic diseases ... Arthritis: • Joint ... arthropathy • 90% joints
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... overlaps with RA ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... • Inner ear • Skin ... of joint cartilage ... as: • SLE • RA ... Polychondritis #rheumatology
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