14 results
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... hemostasis: - Thrombocytopenia ... • Extremes of age ... #Causes #dermatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
SICU > MICU, ♀, ↑Age ... complex → plt activation ... Clinical Suspicion ... #Diagnosis #Management ... #Treatment #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... sequestration and activation ... without other cause ... Risk factors: Age ... Transfusion #Reactions #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... specifically immune thrombocytopenia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Petechial or purpuric rash ... leukopenia, anemia, and thrombocytopenia ... #Syndrome #Diagnosis ... #Management #Hematology
Acute Generalized Exanthematous Pustulosis (AGEP)

AGEP is largely a clinical diagnosis based on classical skin findings in
a clinical diagnosis ... Causes? ... Elevated white blood ... Clinical Presentation ... Exanthematous #Pustulosis #Dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology