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differential classification anca antibodies antibody antimda5 antimda5dm antinuclear antinxp2 antinxp2dm cryoglobulinemia cryoglobulins dermatologic diseases gpa granulomatosis management oncology pain polyangiitis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
(Antineutrophil ... lupus erythematosus ... dermatomyositis ... #antibodies #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , dermatomyositis ... lupus erythematosus ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
causes arthritis ... vesicular eruption - Joints ... mucositis - Rash ... as systemic lupus ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
rash on the face ... interphalangeal joints ... severity of the disease ... #rheumatology # ... dermatology #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... classification #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Causes: - Idiopathic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... #dermatology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... causes arthritis ... Palpable purpura, joint ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... Muscle atrophy may cause ... had more severe disease ... #rheumatology # ... dermatology
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