ScarletFever trunk pediatrics diagnosis dermatology hematology anemia hemolytic differential autoimmune workup extravascular cold thrombocytosis classification

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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... anemia): ... #Causes #differential ... #diagnosis #hematology ... #anemia

Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
-

Hemolysis - Differential ... Diagnosis Algorithm ... anemia • ... Differential #Diagnosis ... Algorithm #Causes #Hematology

Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
• Enzyme deficiencies ex. G6PD, pyruvate kinase
• Hemoglobinopathies

Differential Diagnosis ... for Hemolytic Anemia ... • AIHA: warm, cold ... #Anemia #Differential ... #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... Agglutination - Cold ... elliptocytosis, autoimmune ... #Anemia #Differential ... #workup #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Viral infection, autoimmune ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential ... #anemia #hematology

Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It

Immunosuppression • Autoimmune ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology

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