17 results
diagnosis differential treatment hematology syndrome hemophagocytic lymphohistiocytosis activation adultonset ana antibodies antinuclear behcet capillary clarksons classification cns coccidiodomycosis conditions demyelinating
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... can mimic common infections ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... /DM), Systemic sclerosis ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... SLE], AOSD) • Infection ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Diaqnoses: • Infectious ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
exudates) - SLE • Scleritis ... Bacterial or viral infection ... Pulmonary ... syndrome - SLE Neurologic ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... , particularly scleritis ... affects the skin, neurologic ... cognitive impairment, neurologic ... Differential #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... extrapulmonary disease ... fungal stain of clinical ... Fungal #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... skin injury) • Neurologic ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... subtypes: - Nodular sclerosis ... number of sites of disease ... #oncology #management
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