65 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
disease characterized ... skin thickening Signs ... interstitial lung disease ... #SSc #rheumatology ... #diagnosis #signs
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... sclerosis/scleroderma ... sclerosis/scleroderma ... ANA #patterns #rheumatology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... (Scleroderma) ... @AnnKumfer #Systemic ... #diagnosis #signs ... #symptoms #rheumatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail ... Abnormality • SLE • Scleroderma ... Iron deficiency anemia ... disease severe ... Differential #Diagnosis #Algorithm
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
sclerosis/scleroderma ... sclerosis/scleroderma ... sclerosis/scleroderma ... Sclerosis (scleroderma ... ANA #patterns #rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Differential Diagnosis Algorithm ... Signs of anemia ... Differential #Diagnosis #Algorithm ... #hematology
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm ... Differential #Diagnosis #Hematology
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
- Kawasaki disease ... central nervous system ... - systemic ... - scleroderma ... Vessels #Diagnosis #Rheumatology
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
Cutaneous and Systemic ... Systemic Findings ... Interstitial lung disease ... tract - Cardiac disease ... Dermatomyositis #Diagnosis #Rheumatology