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diagnosis management leukemia anemia aplastic chronic cll cutaneous dermatology differential erythematosus fungal hemeonc hemophagocytic hlh infections infectiousdiseases lupus lymphocytic lymphohistiocytosis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... most frequent skin ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic ... Syndromes (MDS) ... age 70 years Symptoms ... just beneath the skin ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP Score ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Hepatomegaly • Skin ... diagnosis #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... erythematosus (SCLE ... Clinical Features ... Induced Lupus: • Symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... fungal stain of clinical ... Inhalation of spores ... Aspergillosis Pathophysiology ... , scalp, vagina,
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... Common Signs and Symptoms ... Pathophysiology ... molecular diagnosis: HScore ... Diagnosis #Management #Hematology
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