19 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... #management #treatment
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... : • Clinical Suspicion ... → Calculate 4T score ... • If 4T score ... #Hematology #HemeOnc
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... hyperinflammatory syndrome caused ... Clinical Presentation ... Pathophysiology ... #Management #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... ) Differential Diagnosis ... Maternal Support - Critical ... #management #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... #Management #dermatology
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
70 M chronic scaly ... Diagnosis? ... dermatophytes cause ... Variety #type #clinical ... #photo #foot #dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... malignancy Pathophysiology ... adenoma, ↓(TFT, LH ... or refractory cases ... #Treatment #Pathophysiology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology