16 results
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
with overlying scale ... thick silvery scale ... Auspitz sign, Koebner's ... Papulosquamous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
greasy yellow-brown scale ... associated with signs ... Elbows, knees, scalp ... honey-colored crusts ... ; pruritis #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Diagnosis: HLH signs ... Hemophagocytic #Lymphohistiocytosis ... #diagnosis #management ... #treatment #hematology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... Hemophagocytic #Lymphohistiocytosis ... #diagnosis #management ... treatment #summary #rheumatology
Psoriasiform Scalp Findings in Dermatomyositis

Scalp: DM patients can present with a psoriasiform scalp eruption characterized redness,
Psoriasiform Scalp ... the presenting sign ... in some cases. ... #sign #SkinRash ... Dermatomyositis #Dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... → Calculate 4T score ... • If 4T score ... #Treatment #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... Options for severe cases ... Hemophagocytic #Lymphohistiocytosis ... HLH #Treatment #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology