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diagnosis hlh lymphohistiocytosis product algorithm causes coagulation criticalcare dic differential disseminated foamed fungal hemeonc infections infectiousdiseases intravascular mycoses rheumatology summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... Phagocytosis of blood ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
eruptions, diarrhea, liver ... contamination: Platelets (stored ... RBCs (stored at ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
eruptions, diarrhea, liver ... contamination: Platelets (stored ... RBCs (stored at ... Transfusions #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... #management #hematology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... in the liver along ... beta-oxidation in the liver ... enough to prevent blood ... differential #algorithm #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... - Elevated liver ... Pathophysiology ... #HLH #Hemophagocytic ... #Hematology #HemeOnc
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Major blood ... Aspergillosis Pathophysiology ... throat, skin, scalp ... have positive blood ... Fungal #Diagnosis #Management
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