2159 results
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... = Arrhythmia, seizure ... #Tumor #Lysis #Syndrome ... #TLS #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... #SideEffects #Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... dysfunction: myoclonic seizure ... AlzheimersDisease #Dementia #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... hyperviscosity syndrome ... : • Pathophysiology ... dysrhythmias, seizures
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Headache • Seizures ... • Headache • Seizures ... Etiology: • Pathophysiology ... Constipation, Seizures ... 2-3 mEq/L • Seizures
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Movement disorders, Seizure ... Disease, PRES Pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... Rhabdomyolysis • Seizures ... • Nephrotic syndrome ... #Refeeding #Syndrome ... Differential #Diagnosis #Pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... exertion/training, Seizures ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... respiratory distress syndrome ... cerebral hemorrhage, seizure
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... • Bartter syndrome ... tachycardia • Seizures ... nephrology #management #pathophysiology