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algorithm causes disorders hyperpigmentation oncology rheumatology agglutinin alopecia anemia arterial cold embolism focal hairloss hypopigmentation lesions leukemia monoclonal nonpalpable palpable
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Leukocytoclastic Vasculitis Secondary ... Petechiae, Palpable purpura ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... Diagnosis #hematology ... #nonpalpable #dermatology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Diagnosis Algorithm ... Tanning • Adverse cutaneous ... • Addison's disease ... McCune Albright syndrome ... #dermatology #Differential
Skin Hyperpigmentation - Differential Diagnosis Algorithm Diffuse: • Tanning • Adverse cutaneous drug eruption • Addison's disease
Diffuse: • Tanning ... • Adverse cutaneous ... • Addison's disease ... McCune Albright syndrome ... #dermatology #Differential
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... • Loose anagen syndrome ... to Skin Disease ... HairLoss #Alopecia #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... presentation) • Cutaneous ... Diagnosis: • hemolytic ... younger pts) Differential ... #hematology #diagnosis
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential ... Diagnosis Framework ... SAPHO syndrome ( ... Secondary syphilis ... #Diagnosis #Dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Myeloproliferative disease ... Testosterone - Coumadin skin ... • Nephrotic Syndrome ... other causes of purpura ... #hematology #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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