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diagnosis algorithm anemia arterial common cvid embolism extravascular hemolysis hypogammaglobulinemia immunology intravascular management neutropenia nonpalpable nutrition palpable refeeding rheumatology thrombocytopenia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... Diagnosis #hematology ... #nonpalpable #dermatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
thrombocytopenic purpura ... /hemolytic uremic ... syndrome. ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura ... uremic syndrome ... #differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Diagnosis Secondary ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #hematology #secondary
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... noninfectious complications ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... Thrombocytopenic Purpura ... decrease in most cases ... WBC count and differential ... Diagnosis #Workup #Hematology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical complications ... • Seizures • Hemolysis ... hyperparathyroidism • Secondary ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Chediak-Higashi syndrome ... drug reactions - Secondary ... vascular disorders - Immunodeficiency ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... of purpura fulminans ... Venous #Arterial #pathophysiology ... #hematology #differential
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