7 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura ... uremic syndrome ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... Diagnosis #hematology ... palpable #nonpalpable ... #dermatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
/HUS indicates thrombotic ... thrombocytopenic purpura ... /hemolytic uremic ... syndrome. ... thrombocytopenia, Hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... HUGE treatment implications ... thrombocytopenic #purpura ... Comparison #Diagnosis #Table ... #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... of purpura fulminans ... Venous #Arterial #pathophysiology ... #hematology #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... Thrombocytopenic Purpura ... decrease in most cases ... WBC count and differential ... Diagnosis #Workup #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary infiltrates, hemoptysis ... infiltrates/cavities, hemoptysis ... tract, and often causes ... Thrombosis and arterial