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causes differential rhabdomyolysis diuresis diuretics encephalopathy excretion gitelman hematology k leukostasis lysis medications neurology pharmacology posterior potassium pres reversible summary
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... #diagnosis #nephrology ... #management #pathophysiology ... #Hypokalemia
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... or induced) #Hypokalemia ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... • LDH ↑ • Hyperkalemia ... Dialysis for severe hyperkalemia ... #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... emcrit.org/ibcc/hyperkalemia ... of hyperkalemia ... #Hyperkalemia ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management ... Dermatomyositis) AKI ... - Pathophysiology ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... , Elevated Cr, Low ... hydration - Hyperkalemia ... #TLS #diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Metabolic alkalosis ... • Diagnosis of ... irrigation • Management ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents, Renal ... Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... #diagnosis #management ... #neurology
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