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management differential causes rhabdomyolysis diuresis diuretics excretion gitelman hyperkalemia hyponatremia hypotonic k leukostasis lysis medications pharmacology physiologic potassium sodium summary
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
• Normal or low ... (renal potassium ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... declines > ALT) • AKI ... + myoglobin AKI ... per day until stable ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Dermatomyositis) AKI ... - Pathophysiology ... per day until stable ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , Elevated Cr, Low ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , RTA Type IV, AI ... Elimination (see Table ... acidosis) • Low ... #nephrology #K
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Metabolic alkalosis ... • Diagnosis of ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Medications #Table
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